PHARMADRY® 真空臥式槳葉干燥機(jī)

主要是原料藥和精細(xì)化工產(chǎn)品的干燥的PHARMADRY®臥式真空槳葉干燥機(jī)。 除了其較低的資本投資成本，本機(jī)的主要優(yōu)點(diǎn)是其短的周期時(shí)間，防止異物污染，操作簡單，容易驗(yàn)證，以及促進(jìn)清潔和檢查。 的干衣機(jī)，特別適合于使用在潔凈室和無菌應(yīng)用。該機(jī)器設(shè)計(jì)和建造的每cGMP和FDA的指導(dǎo)方針。

的PHARMADRY®的重要特點(diǎn)是： •平焊回平蓋和鉸鏈前門開在整個(gè)血管直徑的圓柱型，臥式容器。當(dāng)門打開時(shí)，機(jī)器內(nèi)部的清洗和檢查的目的完全訪問。 •與產(chǎn)品如容器接觸的所有表面，后蓋，前門，攪拌器和蒸汽過濾器被加熱時(shí)，提供了非常有效的熱交換。 •的圓筒形容器中，后蓋，前門和攪拌器的加工，以保證^小的可能的攪拌器和血管壁之間的公差。 •^小公差也可以很好的熱交換，防止產(chǎn)品合規(guī)性。 •所有內(nèi)表面鏡面拋光處理，以提高流動(dòng)行為的預(yù)防口服amiodarone粉狀產(chǎn)品，以及以方便清潔。 •攪拌器被安裝在干衣機(jī)的背面，該船只的一側(cè)上支持  - 攪拌器設(shè)計(jì)以滿足要求的這個(gè)特定干燥器類型，以保證良好的混合均勻的行動(dòng)整個(gè)干燥器體積，也反向操作，以提供良好的放電特性，并在相同的時(shí)間，減少摩擦至^小，以在產(chǎn)品上防止局部過熱，以及防止推力或本地產(chǎn)品壓縮。  - 加快電動(dòng)驅(qū)動(dòng)或液壓傳動(dòng)與控制閥的可調(diào)使用頻率轉(zhuǎn)換器，  - 攪拌軸密封采用雙端面機(jī)械密封或填料函。

•機(jī)械密封機(jī)械密封 安裝在后蓋，非常便于清潔和維護(hù)的目的。干或濕的正在運(yùn)行的機(jī)械密封可以安裝。

•機(jī)械密封的優(yōu)點(diǎn)：  - 更好的^終真空  - 沒有危險(xiǎn)的泄漏或排放  - 沒有產(chǎn)品污染  - 無菌操作的可能性  - 故障檢測(cè)系統(tǒng)的機(jī)械    密封

•有多個(gè)唇式密封填料箱要求不高的應(yīng)用程序。 •固體排放閥，插頭或球型，氣動(dòng)操作。

•CIP和/或可用的蒸汽滅菌 •蒸汽過濾器，配有自動(dòng)過濾器后清洗系統(tǒng)。 •進(jìn)樣閥 •可選的菜刀 •計(jì)算機(jī)控制手冊(cè)，或與PLC，PC和DCS •電子預(yù)接線的機(jī) •設(shè)計(jì)和制造，如ASME，TUV等國際組織的要求 •無害環(huán)境和安全操作

PHARMADRY® Vacuum horizontal paddle dryer

The PHARMADRY® horizontal vacuum paddle dryer was primarily developed for  the drying of pharmaceutical ingredients and fine chemicals. Besides its low capital investment costs major advantages of this dryer are its short cycle times, the prevention of contamination by foreign matter, its simple operation and easy validation as well as facilitated cleaning and inspection. The dryer is particularly suited to be used in clean rooms and for sterile applications. The machines are designed and built per cGMP and FDA guidelines.

The important features of the PHARMADRY® are: •  Cylindrical, horizontal vessel with flat welded back cover and a hinged flat front door opening up over the entire vessel diameter. With the door open, the internals of the machine are fully accessible for cleaning and inspection purposes. •  All surfaces in contact with the product such as the vessel, back cover, front door, agitator and vapour filter are heated, providing very efficient heat exchange. •  The cylindrical vessel, the back cover, the front door and the agitator are machined to assure the smallest possible tolerances between agitator and vessel walls. •  Smallest possible tolerances also permit good heat exchange and prevent product adherence. •  All internal surfaces are mirror polished, to improve the flow behaviour of powdery products, the prevention of microdeposits as well as to facilitate cleaning. •  The agitator is installed at the back of the dryer, supported on one side of the vessel only -  The agitator is designed to meet the requirements of this particular dryer type to assure good and even mixing action throughout the dryer volume, also in reverse operation, to provide good discharging characteristics and at the same time reduce friction on the product to a minimum to prevent local overheating as well as to prevent directional thrust or local product compression. -  Speed adjustable using frequency converters with electric drives or control valves with hydraulic drives -  Sealing of the agitator shaft with double mechanical seal or stuffing box.

•  Mechanical seal: the mechanical seal is installed on the rear cover, and is well accessible for cleaning and maintenance purposes. Dry or wet running mechanical seals may be installed.

•  Advantages of the mechanical seal: -  Better final vacuum -  No hazardous leakage or emissions -  No product contamination -  Possibility of sterile operation -  Failure detection system for mechanical    seal

•  Stuffing box with multiple lip seals for undemanding applications. •  Solids discharge valve, plug or ball type, pneumatically operated.

•  CIP and / or steam sterilization available •  Vapour filter, equipped with automatic filter back-cleaning system. •  Sample valve •  Optional choppers •  Machine controls manual, or with PLC, PC and DCS •  Electric pre-wiring of machine •  Design and manufacturing to the requirements of international organizations such as ASME, TÜV, etc. •  Environmentally sound and safe to operate